SHAP Analysis and Comparative Performance of the HEART, HET, and SVEAT Scores in 30-Day MACE Prediction
Ali Sarıdaş, Ömerul Faruk Aydin
American Journal of Emergency Medicine, May 6, 2025
✅ Conclusion:
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HEART score remains the most accurate and useful tool for predicting 30-day MACE in ED patients with chest pain.
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HET score performs comparably, while SVEAT is less accurate.
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SHAP analysis reinforces the diagnostic value of HEART score components.
🧪 Methods:
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Design: Retrospective cohort study
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Population: 1,330 ED patients with chest pain
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Outcome: 30-day MACE (12.6% incidence)
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Analysis tools:
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AUROC (discrimination)
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NRI and IDI (reclassification/discrimination improvement)
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SHAP (machine learning feature contribution)
📊 Key Results:
|
Score |
AUROC (95% CI) |
Performance Rank |
|
HEART |
0.872 (0.853–0.890) |
Best |
|
HET |
0.859 (0.840–0.878) |
Second |
|
SVEAT |
0.823 (0.802–0.844) |
Lowest |
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No significant difference between HEART and HET (p = 0.0787) -
HEART and HET both outperformed SVEAT (p < 0.001 for each)
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SHAP analysis: HEART score variables had the strongest individual contributions to MACE prediction
Sarıdaş, A. and Aydin, Ö.F., 2025. SHAP analysis and comparative performance of the HEART, HET, and SVEAT scores in 30-day MACE prediction. The American Journal of Emergency Medicine.