Can Intubate, Cannot Ventilate: A Proposed Algorithm for Post-Intubation Ventilation and Oxygenation Issues

Can Intubate, Cannot Ventilate: A Proposed Algorithm for Post-Intubation Ventilation and Oxygenation Issues

Authors: Kjetil Fosse, Magnus Salomonsen, Sven Erik Gisvold, Bjørnar Gundersen, Trond Nordseth
Journal: Acta Anaesthesiologica Scandinavica, March 2025

Conclusions:

  • The CICV scenario is a critical emergency that requires a structured approach.

  • Key principles: Rule out equipment failure and airway obstruction before diagnosing medical causes of ventilatory failure.

  • The proposed algorithm provides a stepwise approach for rapid evaluation and intervention to improve ventilation and oxygenation post-intubation.

Proposed Algorithm for CICV

In an intubated patient, the airway should be assessed as a continuum from the ventilator to the alveoli, and the problem can occur at any level:

Ventilator → Hoses → Filter → Tracheal Tube (TT) → Trachea → Bronchi → Bronchioles → Alveoli

1️⃣ Confirm Correct Endotracheal Tube (ETT) Placement

  • Primary marker: Positive capnography waveform

  • Further confirmation: Direct or video laryngoscopy

  • If uncertain: Remove ETT and reintubate

2️⃣ Disconnect from Ventilator & Manually Ventilate

  • Use bag-valve-mask (BVM) with 100% oxygen

  • If chest rise is absent → Perform immediate airway assessment

3️⃣ Check for Equipment or Airway Obstruction

  • Verify an open ETT by passing a suction catheter through the tube

  • Inspect ventilator hoses, filters, and tubing for blockages

  • If obstruction is suspected but cannot be cleared, replace ETT

4️⃣ Consider & Treat Differential Diagnoses

  • Bronchospasm: Listen for wheezing, treat with bronchodilators

  • Anaphylaxis: Administer epinephrine if allergic reaction suspected

  • Pneumothorax: Assess for absent breath sounds, perform needle decompression if indicated

5️⃣ Optimize Gas Exchange & Circulation

  • Reassess oxygenation & ventilation strategy

  • If no improvement, consider advanced interventions (e.g., proning, ECMO referral in refractory hypoxia)


Fosse, K., Salomonsen, M., Gisvold, S.E., Gundersen, B. and Nordseth, T., 2025. Can intubate, cannot ventilate: A proposed algorithm to handle problems with ventilation and oxygenation after intubation. Acta Anaesthesiologica Scandinavica, 69(3), p.e70007.

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